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Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular sorts with recombination functionality.

Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I

Our get the job done was immediately adopted up by Many others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.

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Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-movie voltammetry

Considering that 2000 he moved to single-molecule biophysics and nanobiology, with research from DNA supercoiling experiments of nucleosomes and DNA repair service proteins to DNA translocation by way of nanopores. Not too long ago his study has centered on finding out cell division with microbes on chip, even though his supreme curiosity is in the course of acknowledging artificial cells.

2000, discovery that nanotubes can carry remarkable significant existing densities; resolved the controversial concern of Digital transportation via DNA molecules by measurements of insulating habits at The one molecule level; and demonstration of an AFM strategy for one-molecule manipulation of nanotubes

‘You shouldn't just think of the inquiries of tomorrow, and also look at the inquiries on the day right after tomorrow’

1). The existing–voltage curves showed sizeable modulations with gate voltage, even at space temperature, which was in line with band bending in a very ~0.6 eV bandgap semiconducting nanotube. These knowledge also confirmed that the conductance may very well be modulated by six orders of magnitude by transforming the gate voltage. The results of this do the job — a space-temperature transistor constructed from just one carbon nanotube molecule — ended up published in Character in May perhaps 1998.

[14] In 2005 Dekker grew to become linked to Netherlands-extensive conversations about Intelligent Style and design, a movement that he has considering that clearly distanced himself from. Dekker advocates that science and religion are usually not in opposition but could be harmonized.

Cees Dekker is Distinguished University Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Since 2000, he moved to single-molecule biophysics and nanobiology. His latest exploration focuses on (i) nanopores for protein sequencing; (ii) chromosome framework, especially SMC motor protein; and (iii) creating a living artificial mobile from lifeless molecules. Dekker is really an elected member with the KNAW and fellow on the APS along with the IOP.

2008, initially observation of protein-coated DNA translocation by nanopores; solved the origin on the electrophoretic pressure on DNA in nanopores; uncovered a major velocity boost of microtubules in electric fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid

2004, discovery of recent ceesdekker physics in translocation of DNA by nanopores; very first experimental study of ions conduction in nanofluidic channels; initially electrochemistry with personal one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; first electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization in the mechanical properties of double-stranded RNA; and 1st single-molecule review of DNA translocation by a restriction-modification enzyme.